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A fully human transgene switch to regulate therapeutic protein production by cooling sensation.
Bai, Peng; Liu, Ying; Xue, Shuai; Hamri, Ghislaine Charpin-El; Saxena, Pratik; Ye, Haifeng; Xie, Mingqi; Fussenegger, Martin.
Affiliation
  • Bai P; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Liu Y; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Xue S; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
  • Hamri GC; Département Génie Biologique, Institut Universitaire de Technologie de Lyon 1, Villeurbanne, France.
  • Saxena P; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Ye H; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
  • Xie M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
  • Fussenegger M; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland. fussenegger@bsse.ethz.ch.
Nat Med ; 25(8): 1266-1273, 2019 08.
Article in En | MEDLINE | ID: mdl-31285633
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transgenes / Activin Receptors, Type II / TRPM Cation Channels / Insulin Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2019 Document type: Article Affiliation country: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transgenes / Activin Receptors, Type II / TRPM Cation Channels / Insulin Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2019 Document type: Article Affiliation country: Switzerland