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Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial.
Di, Wei-Li; Lwin, Su M; Petrova, Anastasia; Bernadis, Catina; Syed, Farhatullah; Farzaneh, Farzin; Moulding, Dale; Martinez, Anna E; Sebire, Neil J; Rampling, Dyanne; Virasami, Alex; Zamiri, Mozheh; Wang, Wei; Hara, Havinder; Kadiyirire, Tendai; Abdul-Wahab, Alya; Martinez-Queipo, Magdalena; Harper, John I; McGrath, John A; Thrasher, Adrian J; Mellerio, Jemima E; Qasim, Waseem.
Affiliation
  • Di WL; Infection, Immunity and Inflammation Programme, UCL GOS Institute of Child Health, London, United Kingdom.
  • Lwin SM; St. John's Institute of Dermatology, King's College London, Guy's Hospital, London, United Kingdom.
  • Petrova A; Infection, Immunity and Inflammation Programme, UCL GOS Institute of Child Health, London, United Kingdom.
  • Bernadis C; Plastic Surgery Unit, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.
  • Syed F; Infection, Immunity and Inflammation Programme, UCL GOS Institute of Child Health, London, United Kingdom.
  • Farzaneh F; Cell and Gene Therapy-King's (CGT-K), School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Moulding D; Light Microscopy Core Facility, UCL GOS Institute of Child Health, London, United Kingdom.
  • Martinez AE; Dermatology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
  • Sebire NJ; Histopathology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
  • Rampling D; Histopathology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
  • Virasami A; Histopathology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
  • Zamiri M; School of Life Sciences, University of Dundee, Scotland, United Kingdom.
  • Wang W; Department of Translational Oncology, German Cancer Research Center, National Center for Tumor Diseases, Heidelberg, Heidelberg, Germany.
  • Hara H; GeneWerk GmbH, Heidelberg, Germany.
  • Kadiyirire T; Infection, Immunity and Inflammation Programme, UCL GOS Institute of Child Health, London, United Kingdom.
  • Abdul-Wahab A; St. John's Institute of Dermatology, King's College London, Guy's Hospital, London, United Kingdom.
  • Martinez-Queipo M; St. John's Institute of Dermatology, King's College London, Guy's Hospital, London, United Kingdom.
  • Harper JI; St. John's Institute of Dermatology, King's College London, Guy's Hospital, London, United Kingdom.
  • McGrath JA; Infection, Immunity and Inflammation Programme, UCL GOS Institute of Child Health, London, United Kingdom.
  • Thrasher AJ; St. John's Institute of Dermatology, King's College London, Guy's Hospital, London, United Kingdom.
  • Mellerio JE; Infection, Immunity and Inflammation Programme, UCL GOS Institute of Child Health, London, United Kingdom.
  • Qasim W; St. John's Institute of Dermatology, King's College London, Guy's Hospital, London, United Kingdom.
Hum Gene Ther ; 30(9): 1067-1078, 2019 09.
Article in En | MEDLINE | ID: mdl-31288584
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transduction, Genetic / Transgenes / Epidermis / Netherton Syndrome / Epidermal Cells Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Hum Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transduction, Genetic / Transgenes / Epidermis / Netherton Syndrome / Epidermal Cells Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Hum Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United States