Rifampicin induces clathrin-dependent endocytosis and ubiquitin-proteasome degradation of MRP2 via oxidative stress-activated PKC-ERK/JNK/p38 and PI3K signaling pathways in HepG2 cells.
Acta Pharmacol Sin
; 41(1): 56-64, 2020 Jan.
Article
in En
| MEDLINE
| ID: mdl-31316180
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rifampin
/
Signal Transduction
/
Clathrin
/
Oxidative Stress
/
Multidrug Resistance-Associated Proteins
/
Ubiquitin
/
Proteasome Endopeptidase Complex
/
Endocytosis
Limits:
Humans
Language:
En
Journal:
Acta Pharmacol Sin
Journal subject:
FARMACOLOGIA
Year:
2020
Document type:
Article
Affiliation country:
China