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Evaluation of a health service adopting proactive approach to reduce high risk of lung cancer: The Liverpool Healthy Lung Programme.
Ghimire, Bhagabati; Maroni, Roberta; Vulkan, Daniel; Shah, Zoheb; Gaynor, Edward; Timoney, Michelle; Jones, Lisa; Arvanitis, Rachel; Ledson, Martin; Lukehirst, Linda; Rutherford, Paul; Clarke, Faye; Gardner, Katy; Marcus, Michael W; Hill, Sarah; Fidoe, Darcy; Mason, Sabrina; Smith, Samuel G; Quaife, Samantha L; Fitzgerald, Karen; Poirier, Veronique; Duffy, Stephen W; Field, John K.
Affiliation
  • Ghimire B; Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK. Electronic address: bhagabati.ghimire@kcl.ac.uk.
  • Maroni R; Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK.
  • Vulkan D; Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK.
  • Shah Z; Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK.
  • Gaynor E; National Health Service (NHS) Liverpool Clinical Commissioning Group, UK.
  • Timoney M; National Health Service (NHS) Liverpool Clinical Commissioning Group, UK.
  • Jones L; National Health Service (NHS) Liverpool Clinical Commissioning Group, UK.
  • Arvanitis R; National Health Service (NHS) Liverpool Clinical Commissioning Group, UK.
  • Ledson M; Liverpool Heart and Chest Hospital, UK.
  • Lukehirst L; Liverpool Heart and Chest Hospital, UK.
  • Rutherford P; Liverpool Heart and Chest Hospital, UK.
  • Clarke F; Liverpool Heart and Chest Hospital, UK.
  • Gardner K; Macmillan General Practitioner, NHS Liverpool Clinical Commissioning Group, UK.
  • Marcus MW; Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, UK.
  • Hill S; Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, UK.
  • Fidoe D; Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, UK.
  • Mason S; Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, UK.
  • Smith SG; Leeds Institute of Health Sciences, University of Leeds, UK.
  • Quaife SL; Research Department of Behavioural Science and Health, University College London, UK.
  • Fitzgerald K; Accelerate, Coordinate, Evaluate (ACE) team, Cancer Research, UK.
  • Poirier V; Accelerate, Coordinate, Evaluate (ACE) team, Cancer Research, UK.
  • Duffy SW; Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK.
  • Field JK; Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, UK.
Lung Cancer ; 134: 66-71, 2019 08.
Article in En | MEDLINE | ID: mdl-31319997
ABSTRACT

OBJECTIVES:

This Liverpool Healthy Lung Programme is a response to high rates of lung cancer and respiratory diseases locally and aims to diagnose lung cancer at an earlier stage by proactive approach to those at high risk of lung cancer. The objective of this study is to evaluate the programme in terms of its likely effect on mortality from lung cancer and its delivery to deprived populations.

METHODS:

Persons aged 58-75 years, with a history of smoking or a diagnosis of chronic obstructive pulmonary disease (COPD)2 according to general practice records were invited for lung health check in a community health hub setting. A detailed risk assessment and spirometry were performed in eligible patients. Those with a 5% or greater five-year risk of lung cancer were referred for a low dose CT3 scan.

RESULTS:

A total of 4 566 subjects attended the appointment for risk assessment and 3 591 (79%) consented to data sharing. More than 80% of the patients were in the most deprived quintile of the index of multiple deprivation. Of those attending, 63% underwent spirometry and 43% were recommended for a CT scan. A total of 25 cancers were diagnosed, of which 16 (64%) were stage I. Comparison with the national stage distribution implied that the programme was reducing lung cancer mortality by 22%.

CONCLUSIONS:

Community based proactive approaches to early diagnosis of lung cancer in health deprived regions are likely to be effective in early detection of lung cancer.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Community Health Services / Early Detection of Cancer / Lung Neoplasms Type of study: Diagnostic_studies / Etiology_studies / Evaluation_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspects: Implementation_research Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Lung Cancer Journal subject: NEOPLASIAS Year: 2019 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Community Health Services / Early Detection of Cancer / Lung Neoplasms Type of study: Diagnostic_studies / Etiology_studies / Evaluation_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspects: Implementation_research Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Lung Cancer Journal subject: NEOPLASIAS Year: 2019 Document type: Article