Language impairment in progressive supranuclear palsy and corticobasal syndrome.
J Neurol
; 268(3): 796-809, 2021 Mar.
Article
in En
| MEDLINE
| ID: mdl-31321513
ABSTRACT
Although commonly known as movement disorders, progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) may present with changes in speech and language alongside or even before motor symptoms. The differential diagnosis of these two disorders can be challenging, especially in the early stages. Here we review their impact on speech and language. We discuss the neurobiological and clinical-phenomenological overlap of PSP and CBS with each other, and with other disorders including non-fluent agrammatic primary progressive aphasia and primary progressive apraxia of speech. Because language impairment is often an early and persistent problem in CBS and PSP, there is a need for improved methods for language screening in primary and secondary care, and more detailed language assessments in tertiary healthcare settings. Improved language assessment may aid differential diagnosis as well as inform clinical management decisions.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Supranuclear Palsy, Progressive
/
Language Development Disorders
Type of study:
Prognostic_studies
/
Qualitative_research
Limits:
Humans
Language:
En
Journal:
J Neurol
Year:
2021
Document type:
Article
Affiliation country:
United kingdom