Assessing the Lifetime Cost-Effectiveness of Low-Protein Infant Formula as Early Obesity Prevention Strategy: The CHOP Randomized Trial.
Nutrients
; 11(7)2019 Jul 19.
Article
in En
| MEDLINE
| ID: mdl-31331027
ABSTRACT
BACKGROUND:
Although there is a growing number of early childhood obesity prevention programs, only a few of them are effective in the long run. Even fewer reports exist on lifetime cost-effectiveness of early prevention strategies. This paper aimed to assess the lifetime cost-effectiveness of infant feeding modification aiming at reducing risk of later obesity.METHODS:
The simulation model consists of two parts (a) Model I used data from the European Childhood Obesity Project (CHOP) trial (up to 6 years) and the German Interview and Examination Survey for Children (KiGGS) (6-17 years) to evaluate BMI trajectories of infants receiving either lower protein (LP) or higher protein (HP) content formula; and (b) Model II estimated lifetime cost-effectiveness based on Model I BMI trajectories. Compared to HP formula, LP formula feeding would incur lower costs that are attributable to childhood obesity across all decades of life.RESULTS:
Our analysis showed that LP formula would be cost-effective in terms of a positive net monetary benefit (discounted 3%) as an obesity prevention strategy. For the 19% of infants fed with formula in Germany, the LP strategy would result in cost savings of 2.5 billion.CONCLUSIONS:
Our study is one of the first efforts to provide much-needed cost-effectiveness evidence of infant feeding modification, thereby potentially motivating interventionists to reassess their resource allocation.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cost-Benefit Analysis
/
Diet, Protein-Restricted
/
Infant Formula
/
Pediatric Obesity
Type of study:
Clinical_trials
/
Health_economic_evaluation
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Newborn
Country/Region as subject:
Europa
Language:
En
Journal:
Nutrients
Year:
2019
Document type:
Article
Affiliation country:
Germany