Novel antipsoriatic fluidized spanlastic nanovesicles: In vitro physicochemical characterization, ex vivo cutaneous retention and exploratory clinical therapeutic efficacy.

Elmowafy, Enas; El-Gogary, Riham I; Ragai, Maha H; Nasr, Maha

Elmowafy, Enas; El-Gogary, Riham I; Ragai, Maha H; Nasr, Maha.

Affiliation

Elmowafy E; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
El-Gogary RI; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Ragai MH; Department of Dermatology, STD's and Andrology, Faculty of Medicine, Minia University, Al Minya, Egypt.
Nasr M; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt. Electronic address: drmahanasr@pharma.asu.edu.eg.

Int J Pharm ; 568: 118556, 2019 Sep 10.

Article in En | MEDLINE | ID: mdl-31348982

Subject(s)

Dermatologic Agents/administration & dosage; Eucalyptol/administration & dosage; Nanostructures/administration & dosage; Nicotinic Acids/administration & dosage; Psoriasis/drug therapy; Administration, Cutaneous; Adult; Animals; Female; Hexoses/administration & dosage; Humans; Male; Middle Aged; Polysorbates/administration & dosage; Psoriasis/pathology; Rats; Skin/drug effects; Skin/metabolism; Skin/pathology; Skin Absorption; Treatment Outcome; Young Adult

Key words

Clinical efficacy; Cutaneous retention; Psoriasis; Spanlastic nanovesicles; Tazarotene

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Nanostructures / Dermatologic Agents / Eucalyptol / Nicotinic Acids Limits: Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: Int J Pharm Year: 2019 Document type: Article Affiliation country: Egypt Country of publication: Netherlands

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