Degradation of a monoclonal anti-mu chain antibody in a human surface IgM-positive B cell line starts in prelysosomal vesicle.

Ruud, E; Kindberg, G M; Blomhoff, H K; Godal, T; Berg, T

Ruud, E; Kindberg, G M; Blomhoff, H K; Godal, T; Berg, T.

Affiliation

Ruud E; Immunology Laboratory, Institute for Cancer Research, Oslo, Norway.

J Immunol ; 141(9): 2951-8, 1988 Nov 01.

Article in En | MEDLINE | ID: mdl-3139770

Subject(s)

Antibodies, Anti-Idiotypic/metabolism; Antibodies, Monoclonal/metabolism; B-Lymphocytes/metabolism; Immunoglobulin M/immunology; Immunoglobulin mu-Chains/immunology; Lysosomes/metabolism; Receptors, Antigen, B-Cell/metabolism; Animals; Antibodies, Anti-Idiotypic/isolation & purification; Antibodies, Monoclonal/isolation & purification; B-Lymphocytes/analysis; Biological Transport; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin M/isolation & purification; Immunoglobulin M/metabolism; Immunoglobulin mu-Chains/isolation & purification; Intracellular Fluid/metabolism; Iodine Radioisotopes/metabolism; Macromolecular Substances; Mice; Protease Inhibitors; Subcellular Fractions/metabolism; Temperature

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin M / B-Lymphocytes / Receptors, Antigen, B-Cell / Antibodies, Anti-Idiotypic / Immunoglobulin mu-Chains / Lysosomes / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: J Immunol Year: 1988 Document type: Article Affiliation country: Norway Country of publication: United States

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