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Identification and validation of uterine perforation, intrauterine device expulsion, and breastfeeding in four health care systems with electronic health records.
Anthony, Mary S; Armstrong, Mary Anne; Getahun, Darios; Scholes, Delia; Gatz, Jennifer; Schulze-Rath, Renate; Postlethwaite, Debbie; Merchant, Maqdooda; Alabaster, Amy L; Chillemi, Giulia; Raine-Bennett, Tina; Xie, Fagen; Chiu, Vicki Y; Im, Theresa M; Takhar, Harpreet S; Fassett, Michael; Grafton, Jane; Cronkite, David; Ichikawa, Laura; Reed, Susan D; Hui, Siu Lui; Ritchey, Mary E; Saltus, Catherine W; Andrews, Elizabeth B; Rothman, Kenneth J; Asiimwe, Alex; Lynen, Richard; Schoendorf, Juliane.
Affiliation
  • Anthony MS; RTI Health Solutions , Research Triangle Park, NC, USA.
  • Armstrong MA; Kaiser Permanente Northern California , Oakland, CA, USA.
  • Getahun D; Kaiser Permanente Southern California , Pasadena, CA, USA.
  • Scholes D; Kaiser Permanente Washington , Seattle, WA, USA.
  • Gatz J; Regenstrief Institute , Indianapolis, IN, USA.
  • Schulze-Rath R; Bayer AG , Berlin, Germany.
  • Postlethwaite D; Kaiser Permanente Northern California , Oakland, CA, USA.
  • Merchant M; Kaiser Permanente Northern California , Oakland, CA, USA.
  • Alabaster AL; Kaiser Permanente Northern California , Oakland, CA, USA.
  • Chillemi G; Kaiser Permanente Northern California , Oakland, CA, USA.
  • Raine-Bennett T; Kaiser Permanente Northern California , Oakland, CA, USA.
  • Xie F; Kaiser Permanente Southern California , Pasadena, CA, USA.
  • Chiu VY; Kaiser Permanente Southern California , Pasadena, CA, USA.
  • Im TM; Kaiser Permanente Southern California , Pasadena, CA, USA.
  • Takhar HS; Kaiser Permanente Southern California , Pasadena, CA, USA.
  • Fassett M; Kaiser Permanente Southern California , Pasadena, CA, USA.
  • Grafton J; Kaiser Permanente Washington , Seattle, WA, USA.
  • Cronkite D; Kaiser Permanente Washington , Seattle, WA, USA.
  • Ichikawa L; Kaiser Permanente Washington , Seattle, WA, USA.
  • Reed SD; Kaiser Permanente Washington , Seattle, WA, USA.
  • Hui SL; University of Washington , Seattle, WA, USA.
  • Ritchey ME; Regenstrief Institute , Indianapolis, IN, USA.
  • Saltus CW; RTI Health Solutions , Research Triangle Park, NC, USA.
  • Andrews EB; RTI Health Solutions , Waltham, MA, USA.
  • Rothman KJ; RTI Health Solutions , Research Triangle Park, NC, USA.
  • Asiimwe A; RTI Health Solutions , Waltham, MA, USA.
  • Lynen R; Bayer AG , Berlin, Germany.
  • Schoendorf J; Bayer HealthCare , Whippany, NJ, USA.
Clin Epidemiol ; 11: 635-643, 2019.
Article in En | MEDLINE | ID: mdl-31413641
ABSTRACT

OBJECTIVE:

To validate algorithms identifying uterine perforations and intrauterine device (IUD) expulsions and to ascertain availability of breastfeeding status at the time of IUD insertion. STUDY DESIGN AND

SETTING:

Four health care systems with electronic health records (EHRs) participated Kaiser Permanente Northern California (KPNC), Kaiser Permanente Southern California (KPSC), Kaiser Permanente Washington (KPWA), and Regenstrief Institute (RI). The study included women ≤50 years of age with an IUD insertion. Site-specific algorithms using structured and unstructured data were developed and a sample validated by EHR review. Positive predictive values (PPVs) of the algorithms were calculated. Breastfeeding status was assessed in a random sample of 125 women at each research site with IUD placement within 52 weeks postpartum.

RESULTS:

The study population included 282,028 women with 325,582 IUD insertions. The PPVs for uterine perforation were KPNC 77%, KPSC 81%, KPWA 82%, and RI 47%; PPVs for IUD expulsion were KPNC 77%, KPSC 87%, KPWA 68%, and RI 37%. Across all research sites, breastfeeding status at the time of IUD insertion was determined for 94% of those sampled.

CONCLUSIONS:

Algorithms with a high PPV for uterine perforation and IUD expulsion were developed at 3 of the 4 research sites. Breastfeeding status at the time of IUD insertion could be determined at all research sites. Our findings suggest that a study to evaluate the associations of breastfeeding and postpartum IUD insertions with risk of uterine perforation and IUD expulsion can be successfully conducted retrospectively; however, automated application of algorithms must be supplemented with chart review for some outcomes at one research site due to low PPV.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Clin Epidemiol Year: 2019 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Clin Epidemiol Year: 2019 Document type: Article Affiliation country: United States