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CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.
Tian, Ruilin; Gachechiladze, Mariam A; Ludwig, Connor H; Laurie, Matthew T; Hong, Jason Y; Nathaniel, Diane; Prabhu, Anika V; Fernandopulle, Michael S; Patel, Rajan; Abshari, Mehrnoosh; Ward, Michael E; Kampmann, Martin.
Affiliation
  • Tian R; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA; Biophysics Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94
  • Gachechiladze MA; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.
  • Ludwig CH; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA.
  • Laurie MT; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Hong JY; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA.
  • Nathaniel D; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA.
  • Prabhu AV; National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892, USA.
  • Fernandopulle MS; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.
  • Patel R; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.
  • Abshari M; National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892, USA.
  • Ward ME; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA. Electronic address: wardme@nih.gov.
  • Kampmann M; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: martin.kampmann@ucsf.edu.
Neuron ; 104(2): 239-255.e12, 2019 10 23.
Article in En | MEDLINE | ID: mdl-31422865
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Knockdown Techniques / Induced Pluripotent Stem Cells / CRISPR-Cas Systems / Neurons Limits: Humans Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2019 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Knockdown Techniques / Induced Pluripotent Stem Cells / CRISPR-Cas Systems / Neurons Limits: Humans Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2019 Document type: Article