Carnival: A Graph-Based Data Integration and Query Tool to Support Patient Cohort Generation for Clinical Research.

ABSTRACT

Clinical research studies often leverage various heterogeneous data sources including patient electronic health record, online survey, and genomic data. We introduce a graph-based, data integration and query tool called Carnival. We demonstrate its powerful ability to unify data from these disparate data sources to create datasets for two studies prevalence and incidence case/control matches for coronary artery disease and controls for Marfan syndrome. We conclude with future directions for Carnival development.