Insight into hepatitis B prevalence and risk factors among Vietnamese Americans: a cross-sectional analysis of data from a community-based screening program.
BMJ Open
; 9(8): e029616, 2019 08 26.
Article
in En
| MEDLINE
| ID: mdl-31455706
ABSTRACT
OBJECTIVES:
The aims of our study were to describe current hepatitis B prevalence among Vietnamese Americans and to examine predictors of hepatitis B risk in this specific ethnic community.DESIGN:
Cross-sectional analysis of data from a community-based screening program.SETTING:
This analysis was based on hepatitis screening community events in Southern California.PARTICIPANTS:
2508 Vietnamese Americans in Southern California. OUTCOMEMEASURES:
Serological tests for hepatitis B surface antigen, hepatitis B surface antibody, and total hepatitis B core antibody were used to classify participants as one of four hepatitis B infection statuses currently infected, previously infected, susceptible, or immune due to a previous hepatitis B vaccination.RESULTS:
Across 2508 participants, 9.0% were currently infected with hepatitis B and 17.7% were at risk for hepatitis B. Females and those reporting a previous hepatitis B vaccination were at significant decreased risk of hepatitis B (OR=0.48, 95% CI 0.33 to 0.69 and OR=0.53, 95% CI 0.31 to 0.93, respectively) whereas those born outside of the USA and with a family history of the disease showed substantial increased risk (OR=13.36, 95% CI 1.62 to 110.05 and OR=4.68, 95% CI 2.66 to 8.22, respectively). Among those who reported a previous hepatitis B vaccination, less than half (42.9%) possessed the protective antibodies that result from a hepatitis B vaccination.CONCLUSIONS:
Vietnamese Americans remain disproportionately burdened by hepatitis B. Public health efforts that focus on improving hepatitis B awareness and vaccination knowledge and that are tailored to specific high-risk subgroups, such as immigrants and those with infected family members, could help in addressing the disease's burden in this high-prevalence population.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Asian
/
Hepatitis B
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
America do norte
/
Asia
Language:
En
Journal:
BMJ Open
Year:
2019
Document type:
Article
Affiliation country:
United States