Class-switch recombination to IgA in the Peyer's patches requires natural thymus-derived Tregs and appears to be antigen independent.

Gribonika, Inta; Eliasson, Dubravka Grdic; Chandode, Rakesh K; Schön, Karin; Strömberg, Anneli; Bemark, Mats; Lycke, Nils Y

Gribonika, Inta; Eliasson, Dubravka Grdic; Chandode, Rakesh K; Schön, Karin; Strömberg, Anneli; Bemark, Mats; Lycke, Nils Y.

Affiliation

Gribonika I; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Göteborg, Sweden.
Eliasson DG; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Göteborg, Sweden.
Chandode RK; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Göteborg, Sweden.
Schön K; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Göteborg, Sweden.
Strömberg A; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Göteborg, Sweden.
Bemark M; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Göteborg, Sweden.
Lycke NY; Department of Clinical Immunology and Transfusion Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.

Mucosal Immunol ; 12(6): 1268-1279, 2019 11.

Article in En | MEDLINE | ID: mdl-31501516

Subject(s)

B-Lymphocytes/immunology; Immunoglobulin A/genetics; Immunoglobulin Class Switching; Peyer's Patches/immunology; T-Lymphocytes, Helper-Inducer/immunology; T-Lymphocytes, Regulatory/immunology; Thymus Gland/immunology; Adjuvants, Immunologic/administration & dosage; Adoptive Transfer; Animals; B-Lymphocytes/drug effects; B-Lymphocytes/metabolism; Cells, Cultured; Cholera Toxin/administration & dosage; Coculture Techniques; DNA-Binding Proteins/immunology; DNA-Binding Proteins/metabolism; Immunization; Immunoglobulin A/immunology; Immunoglobulin A/metabolism; Immunoglobulin Class Switching/drug effects; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, SCID; Mice, Transgenic; Neuropilin-1/immunology; Neuropilin-1/metabolism; Ovalbumin/administration & dosage; Peyer's Patches/metabolism; T-Lymphocytes, Helper-Inducer/drug effects; T-Lymphocytes, Helper-Inducer/metabolism; T-Lymphocytes, Helper-Inducer/transplantation; T-Lymphocytes, Regulatory/drug effects; T-Lymphocytes, Regulatory/metabolism; T-Lymphocytes, Regulatory/transplantation; Thymus Gland/drug effects; Thymus Gland/metabolism; Transcription Factors/immunology; Transcription Factors/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peyer's Patches / Thymus Gland / Immunoglobulin A / B-Lymphocytes / T-Lymphocytes, Regulatory / T-Lymphocytes, Helper-Inducer / Immunoglobulin Class Switching Language: En Journal: Mucosal Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Document type: Article Affiliation country: Sweden

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google