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Antibodies to the conserved region of the M protein and a streptococcal superantigen cooperatively resolve toxic shock-like syndrome in HLA-humanized mice.
Pandey, Manisha; Calcutt, Ainslie; Ozberk, Victoria; Chen, Zhenjun; Croxen, Matthew; Powell, Jessica; Langshaw, Emma; Mills, Jamie-Lee; Jen, Freda E-C; McCluskey, James; Robson, Jenny; Tyrrell, Gregory J; Good, Michael F.
Affiliation
  • Pandey M; Institute for Glycomics, Griffith University, Gold Coast, Australia.
  • Calcutt A; Institute for Glycomics, Griffith University, Gold Coast, Australia.
  • Ozberk V; Institute for Glycomics, Griffith University, Gold Coast, Australia.
  • Chen Z; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.
  • Croxen M; Division of Diagnostic and Applied Microbiology, Department of Laboratory Medicine and Pathology, University of Alberta and ProvLab, Edmonton, Canada.
  • Powell J; Institute for Glycomics, Griffith University, Gold Coast, Australia.
  • Langshaw E; Institute for Glycomics, Griffith University, Gold Coast, Australia.
  • Mills JL; Institute for Glycomics, Griffith University, Gold Coast, Australia.
  • Jen FE; Institute for Glycomics, Griffith University, Gold Coast, Australia.
  • McCluskey J; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Australia.
  • Robson J; Sullivan and Nicolaides Pathology, Brisbane, Australia.
  • Tyrrell GJ; Division of Diagnostic and Applied Microbiology, Department of Laboratory Medicine and Pathology, University of Alberta and ProvLab, Edmonton, Canada.
  • Good MF; Institute for Glycomics, Griffith University, Gold Coast, Australia.
Sci Adv ; 5(9): eaax3013, 2019 09.
Article in En | MEDLINE | ID: mdl-31517054

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shock, Septic / Streptococcal Infections / Streptococcus pyogenes / Bacterial Outer Membrane Proteins / Bacterial Proteins / Carrier Proteins / Superantigens / Exotoxins / HLA Antigens / Antibodies, Bacterial Limits: Animals / Humans Language: En Journal: Sci Adv Year: 2019 Document type: Article Affiliation country: Australia Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shock, Septic / Streptococcal Infections / Streptococcus pyogenes / Bacterial Outer Membrane Proteins / Bacterial Proteins / Carrier Proteins / Superantigens / Exotoxins / HLA Antigens / Antibodies, Bacterial Limits: Animals / Humans Language: En Journal: Sci Adv Year: 2019 Document type: Article Affiliation country: Australia Country of publication: United States