Synthesis of the EFG Framework of Tamulamides A and B.
Org Lett
; 21(19): 8027-8030, 2019 10 04.
Article
in En
| MEDLINE
| ID: mdl-31523969
ABSTRACT
Synthesis of the fused polycyclic ether motif comprising the EFG rings of the marine ladder polyethers tamulamides A and B has been achieved via two different etherification strategies. Ultimately, a reductive etherification approach proved most successful due to tolerance of the G ring substitution and provided the EFG 6,7,6 ring system in 58% yield.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Oxocins
/
Marine Toxins
Language:
En
Journal:
Org Lett
Journal subject:
BIOQUIMICA
Year:
2019
Document type:
Article
Affiliation country:
United States