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Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-Candida Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin.
Pricopie, Andreea-Iulia; Ionuț, Ioana; Marc, Gabriel; Arseniu, Anca-Maria; Vlase, Laurian; Grozav, Adriana; Gaina, Luiza Ioana; Vodnar, Dan C; Pîrnau, Adrian; Tiperciuc, Brîndușa; Oniga, Ovidiu.
Affiliation
  • Pricopie AI; Department of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania. pricopie.andreea@umfcluj.ro.
  • Ionuț I; Department of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania. ionut.ioana@umfcluj.ro.
  • Marc G; Department of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania. marc.gabriel@umfcluj.ro.
  • Arseniu AM; Department of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania. borcea.anca@umfcluj.ro.
  • Vlase L; Preclinic Department, Pharmacy Specialization, Faculty of Medicine, Lucian Blaga University of Sibiu, 2A Lucian Blaga Street, 550169 Sibiu, Romania. borcea.anca@umfcluj.ro.
  • Grozav A; Department of Pharmaceutical Technology and Biopharmaceutics, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania. laurian.vlase@umfcluj.ro.
  • Gaina LI; Department of Organic Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania. adriana.ignat@umfcluj.ro.
  • Vodnar DC; Research Center on Fundamental and Applied Heterochemistry, Faculty of Chemistry and Chemical Engineering, "Babes-Bolyai" University, 11 Arany Janos Street, 400028 Cluj-Napoca, Romania. lusi@chem.ubbcluj.ro.
  • Pîrnau A; Department of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 3-5 Manaștur Street, 400372 Cluj-Napoca, Romania. dan.vodnar@usamvcluj.ro.
  • Tiperciuc B; National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donath Street, 400293 Cluj-Napoca, Romania. adrian.pirnau@itim-cj.ro.
  • Oniga O; Department of Pharmaceutical Chemistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 41 Victor Babeș Street, 400012 Cluj-Napoca, Romania. brandu32@yahoo.com.
Molecules ; 24(19)2019 Sep 21.
Article in En | MEDLINE | ID: mdl-31546673
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida / Antifungal Agents Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: Romania Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida / Antifungal Agents Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: Romania Country of publication: Switzerland