Application of parelectric spectroscopy to detect skin cancer-A pilot study.
Skin Res Technol
; 26(2): 234-240, 2020 Mar.
Article
in En
| MEDLINE
| ID: mdl-31549768
ABSTRACT
BACKGROUND:
The early detection of skin cancer is still challenging and calls for objective, fast diagnostic, and ideally non-invasive methods in order to leave the potentially malignant tumor cells unaltered. In this paper, the parelectric spectroscopy was applied to evaluate the potential of a non-invasive detection of basal cell carcinoma (BCC) and malignant melanoma. MATERIALS ANDMETHODS:
A prototype of parelectric spectroscopy was used to investigate non-invasively dipole density and mobility of suspicious skin lesions. The differences in investigated tissue were analyzed compared to pathohistological findings in a clinical study on 51 patients with suspected BCC and malignant melanoma.RESULTS:
The non-invasive parelectric spectroscopy could differentiate between normal skin, BCC, and melanoma but failed to distinguish between different types of skin cancer. The data were normalized to unsuspected nearby skin because the different skin locations influence dipole density and mobility.CONCLUSION:
The results of the pilot study indicate that the parelectric spectroscopy might be an additional, useful non-invasive diagnostic procedure to distinguish between normal skin and skin cancer.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Neoplasms
/
Spectrum Analysis
/
Signal Processing, Computer-Assisted
Type of study:
Diagnostic_studies
/
Screening_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Skin Res Technol
Journal subject:
DERMATOLOGIA
Year:
2020
Document type:
Article
Affiliation country:
Germany