Tramadol Withdrawal in the Setting of Buprenorphine Induction: A Case Report.
J Addict Med
; 14(3): 264-266, 2020.
Article
in En
| MEDLINE
| ID: mdl-31574012
ABSTRACT
Initiating opioid use disorder treatment with buprenorphine conventionally requires the cessation of other opioid medications, including tramadol. Tramadol's spectrum of activity differs from most opioids, acting through serotonin and norepinephrine reuptake inhibition. Here, we report a case of 45-year-old man who experienced a complicated transition from tramadol to buprenorphine. We believe there were similarities to antidepressant discontinuation syndrome, which could be explained by tramadol's serotoninergic activity. Clinicians should be aware of these effects when discontinuing tramadol, even if replacing with another opioid.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Substance Withdrawal Syndrome
/
Tramadol
/
Buprenorphine
/
Analgesics, Opioid
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Addict Med
Year:
2020
Document type:
Article