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Neutralization of insulin by photocleavage under high vacuum.
Schätti, Jonas; Kriegleder, Moritz; Debiossac, Maxime; Kerschbaum, Michael; Geyer, Philipp; Mayor, Marcel; Arndt, Markus; Köhler, Valentin.
Affiliation
  • Schätti J; Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch.
  • Kriegleder M; Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Debiossac M; Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Kerschbaum M; Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Geyer P; Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Mayor M; Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch and Institute of Nanotechnology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany and Lehn Institute of Functional Materials (L
  • Arndt M; Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
  • Köhler V; Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch.
Chem Commun (Camb) ; 55(83): 12507-12510, 2019 Oct 25.
Article in En | MEDLINE | ID: mdl-31576386
ABSTRACT
Charge reduction and neutralization of electro-sprayed peptides are realized by selective gas-phase photocleavage of tailored covalent tags. The concept is demonstrated with four model peptides in positive and negative ion modes and tagged insulin as the largest construct.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Vacuum / Insulin Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2019 Document type: Article Affiliation country: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Vacuum / Insulin Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2019 Document type: Article Affiliation country: Switzerland