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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
Tin, Adrienne; Marten, Jonathan; Halperin Kuhns, Victoria L; Li, Yong; Wuttke, Matthias; Kirsten, Holger; Sieber, Karsten B; Qiu, Chengxiang; Gorski, Mathias; Yu, Zhi; Giri, Ayush; Sveinbjornsson, Gardar; Li, Man; Chu, Audrey Y; Hoppmann, Anselm; O'Connor, Luke J; Prins, Bram; Nutile, Teresa; Noce, Damia; Akiyama, Masato; Cocca, Massimiliano; Ghasemi, Sahar; van der Most, Peter J; Horn, Katrin; Xu, Yizhe; Fuchsberger, Christian; Sedaghat, Sanaz; Afaq, Saima; Amin, Najaf; Ärnlöv, Johan; Bakker, Stephan J L; Bansal, Nisha; Baptista, Daniela; Bergmann, Sven; Biggs, Mary L; Biino, Ginevra; Boerwinkle, Eric; Bottinger, Erwin P; Boutin, Thibaud S; Brumat, Marco; Burkhardt, Ralph; Campana, Eric; Campbell, Archie; Campbell, Harry; Carroll, Robert J; Catamo, Eulalia; Chambers, John C; Ciullo, Marina; Concas, Maria Pina; Coresh, Josef.
Affiliation
  • Tin A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. atin1@jhu.edu.
  • Marten J; Welch Centre for Prevention, Epidemiology and Clinical Research, Baltimore, MD, USA. atin1@jhu.edu.
  • Halperin Kuhns VL; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Li Y; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Wuttke M; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
  • Kirsten H; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
  • Sieber KB; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
  • Qiu C; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
  • Gorski M; Target Sciences-Genetics, GlaxoSmithKline, Collegeville, PA, USA.
  • Yu Z; Department of Medicine and Genetics, University of Pennsylvania, Philadelphia, PA, USA.
  • Giri A; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
  • Sveinbjornsson G; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
  • Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Chu AY; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Hoppmann A; Division of Quantitative Sciences, Department of Obstetrics & Gynecology, Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN, USA.
  • O'Connor LJ; Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.
  • Prins B; deCODE Genetics, Amgen Inc., Reykjavik, Iceland.
  • Nutile T; Department of Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT, USA.
  • Noce D; Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.
  • Akiyama M; Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
  • Cocca M; Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Ghasemi S; Strangeways Research Laboratory, University of Cambridge, Cambridge, UK.
  • van der Most PJ; Institute of Genetics and Biophysics Adriano Buzzati-Traverso-CNR, Naples, Italy.
  • Horn K; Eurac Research, Institute for Biomedicine, Bolzano, Italy.
  • Xu Y; Laboratory for Statistical Analysis, RIKEN Centre for Integrative Medical Sciences, Yokohama (Kanagawa), Japan.
  • Fuchsberger C; Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Sedaghat S; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.
  • Afaq S; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
  • Amin N; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
  • Ärnlöv J; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Bakker SJL; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
  • Bansal N; LIFE Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
  • Baptista D; Department of Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT, USA.
  • Bergmann S; Eurac Research, Institute for Biomedicine, Bolzano, Italy.
  • Biggs ML; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Biino G; Department of Epidemiology and Biostatistics, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.
  • Boerwinkle E; Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan.
  • Bottinger EP; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Boutin TS; Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.
  • Brumat M; School of Health and Social Studies, Dalarna University, Falun, Sweden.
  • Burkhardt R; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Campana E; Division of Nephrology, University of Washington, Seattle, WA, USA.
  • Campbell A; Kidney Research Institute, University of Washington, Seattle, WA, USA.
  • Campbell H; Cardiology, Geneva University Hospitals, Geneva, Switzerland.
  • Carroll RJ; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
  • Catamo E; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Chambers JC; Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.
  • Ciullo M; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Concas MP; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Coresh J; Institute of Molecular Genetics, National Research Council of Italy, Pavia, Italy.
Nat Genet ; 51(10): 1459-1474, 2019 10.
Article in En | MEDLINE | ID: mdl-31578528
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uric Acid / Cardiovascular Diseases / Signal Transduction / Genetic Markers / Polymorphism, Single Nucleotide / Gout / Metabolic Diseases Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uric Acid / Cardiovascular Diseases / Signal Transduction / Genetic Markers / Polymorphism, Single Nucleotide / Gout / Metabolic Diseases Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States