Metabolic profiling of a polyphenolic-rich fraction of Coccinia grandis leaves using LC-ESI-MS/MS and in vivo validation of its antimicrobial and wound healing activities.

Al-Madhagy, Somaia A; Mostafa, Nada M; Youssef, Fadia S; Awad, Ghada E A; Eldahshan, Omayma A; Singab, Abdel Nasser B

Al-Madhagy, Somaia A; Mostafa, Nada M; Youssef, Fadia S; Awad, Ghada E A; Eldahshan, Omayma A; Singab, Abdel Nasser B.

Affiliation

Al-Madhagy SA; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, Egypt. oeldahshan@pharma.asu.edu.eg.

Food Funct ; 10(10): 6267-6275, 2019 Oct 16.

Article in En | MEDLINE | ID: mdl-31584060

Subject(s)

Anti-Bacterial Agents/administration & dosage; Cucurbitaceae/chemistry; Gram-Positive Bacterial Infections/drug therapy; Plant Extracts/administration & dosage; Polyphenols/administration & dosage; Wounds and Injuries/drug therapy; Animals; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/metabolism; Bacillus cereus/drug effects; Bacillus cereus/physiology; Chromatography, High Pressure Liquid; Gram-Positive Bacterial Infections/microbiology; Gram-Positive Bacterial Infections/physiopathology; Humans; Male; Plant Extracts/chemistry; Plant Leaves/chemistry; Polyphenols/chemistry; Polyphenols/metabolism; Rats; Tandem Mass Spectrometry; Wound Healing/drug effects; Wounds and Injuries/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wounds and Injuries / Plant Extracts / Gram-Positive Bacterial Infections / Cucurbitaceae / Polyphenols / Anti-Bacterial Agents Limits: Animals / Humans / Male Language: En Journal: Food Funct Year: 2019 Document type: Article Affiliation country: Egypt

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