SOX2-induced upregulation of lncRNA LINC01510 promotes papillary thyroid carcinoma progression by modulating miR-335/SHH and activating Hedgehog pathway.

Li, Qun; Wang, Xiang-Jun; Jin, Jian-Hong

Li, Qun; Wang, Xiang-Jun; Jin, Jian-Hong.

Affiliation

Li Q; Department of Endocrinology, Linyi Central Hospital, Linyi City, Shandong Province, China.
Wang XJ; Department of Clinical Laboratory, Linyi Central Hospital, Linyi City, Shandong Province, China.
Jin JH; Department of Endocrinology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou City, Zhejiang Province 310007, China. Electronic address: jinjianhonghz@126.com.

Biochem Biophys Res Commun ; 520(2): 277-283, 2019 12 03.

Article in En | MEDLINE | ID: mdl-31590919

Subject(s)

Hedgehog Proteins/metabolism; MicroRNAs/metabolism; RNA, Long Noncoding/metabolism; SOXB1 Transcription Factors/metabolism; Thyroid Cancer, Papillary/metabolism; Thyroid Neoplasms/metabolism; Up-Regulation; Apoptosis; Cell Proliferation; Cell Survival; Humans; RNA, Long Noncoding/genetics; Thyroid Cancer, Papillary/pathology; Thyroid Neoplasms/pathology; Tumor Cells, Cultured

Key words

Hedgehog pathway; LncRNA LINC01510; Metastasis; Papillary thyroid carcinoma; SHH; miR-335

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Neoplasms / Up-Regulation / MicroRNAs / Hedgehog Proteins / SOXB1 Transcription Factors / RNA, Long Noncoding / Thyroid Cancer, Papillary Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2019 Document type: Article Affiliation country: China Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google