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Human signal transducer and activator of transcription 5b (STAT5b) mutation causes dysregulated human natural killer cell maturation and impaired lytic function.
Vargas-Hernández, Alexander; Witalisz-Siepracka, Agnieszka; Prchal-Murphy, Michaela; Klein, Klara; Mahapatra, Sanjana; Al-Herz, Waleed; Mace, Emily M; Carisey, Alexandre F; Orange, Jordan S; Sexl, Veronika; Forbes, Lisa R.
Affiliation
  • Vargas-Hernández A; Department of Pediatrics, Baylor College of Medicine, Houston; Section of Allergy, Immunology, and Retrovirology, Texas Children's Hospital, William T. Shearer Center for Human Immunobiology, Houston.
  • Witalisz-Siepracka A; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna.
  • Prchal-Murphy M; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna.
  • Klein K; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna.
  • Mahapatra S; Section of Allergy, Immunology, and Retrovirology, Texas Children's Hospital, William T. Shearer Center for Human Immunobiology, Houston.
  • Al-Herz W; Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait City.
  • Mace EM; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York.
  • Carisey AF; Department of Pediatrics, Baylor College of Medicine, Houston; Section of Allergy, Immunology, and Retrovirology, Texas Children's Hospital, William T. Shearer Center for Human Immunobiology, Houston.
  • Orange JS; Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York.
  • Sexl V; Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna.
  • Forbes LR; Department of Pediatrics, Baylor College of Medicine, Houston; Section of Allergy, Immunology, and Retrovirology, Texas Children's Hospital, William T. Shearer Center for Human Immunobiology, Houston. Electronic address: lisa.forbes@bcm.edu.
J Allergy Clin Immunol ; 145(1): 345-357.e9, 2020 01.
Article in En | MEDLINE | ID: mdl-31600547

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / STAT5 Transcription Factor / Immunological Synapses / Immunity, Cellular / Mutation Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Allergy Clin Immunol Year: 2020 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / STAT5 Transcription Factor / Immunological Synapses / Immunity, Cellular / Mutation Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Allergy Clin Immunol Year: 2020 Document type: Article Country of publication: United States