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Discovery of prolyl hydroxylase 2 inhibitors with new chemical scaffolds as in vivo active erythropoietin inducers through a combined virtual screening strategy.
Yu, Zhan; Li, Zhihong; Yu, Quanwei; Wang, Zhi; Song, Huilin; Sun, Hanyu; Fan, Rufeng; Bi, Angzhi; Zhang, Jun; Zhang, Xiaojin.
Affiliation
  • Yu Z; The Affiliated Jiangning Hospital of NJMU, Nanjing Medical University (NJMU), Nanjing, China.
  • Li Z; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
  • Yu Q; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
  • Wang Z; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
  • Song H; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
  • Sun H; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
  • Fan R; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
  • Bi A; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
  • Zhang J; Drum Tower Clinical Medical College of NJMU, Nanjing Medical University (NJMU), Nanjing, China.
  • Zhang X; Department of Chemistry, China Pharmaceutical University, Nanjing, China.
Chem Biol Drug Des ; 95(2): 270-278, 2020 02.
Article in En | MEDLINE | ID: mdl-31628888
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythropoietin / Prolyl-Hydroxylase Inhibitors Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythropoietin / Prolyl-Hydroxylase Inhibitors Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom