Laparoscopic nephrectomy in children with Wilms tumor. Considerations after 10 years of experience.
J Biol Regul Homeost Agents
; 33(5 Suppl. 1): 95-103. Special Issue: Focus on Pediatric Nephrology, 2019.
Article
in En
| MEDLINE
| ID: mdl-31630722
ABSTRACT
Despite laparoscopy in children is considered safe and is routinely used for several procedures, even in neonates and in pediatric oncology, its role in the treatment of pediatric renal tumors is still controversial. This study analyzes the results of laparoscopic nephrectomy for Wilms Tumor (WT) in pediatric age compared with open nephrectomy after 10 years of experience in a single centre. From 1993 in our center of reference for pediatric oncology, 30 patients with WT have been treated. We performed 21 open nephrectomy and in the last 10 years 9 laparoscopic nephrectomy. In all patients treated laparoscopically, the same technique made by the same equip was used. Compared with patients treated by open surgery, we did not find a significant difference in terms of outcome and survival. In the open surgery group, two patients had lung relapse while in the other group there was one local relapse. These three children obtained and maintained a second complete remission with chemotherapy. Open surgery complications were a tumor rupture in two cases, and an episode of pancreatitis 10 days after surgery. In the laparoscopic group, there were two conversions to open surgery not considered as complications but a surgical choice for cystic areas present in the tumor. As far as complications and oncologic outcomes are concerned, both techniques showed similar results. In experienced hands, laparoscopy proves to be an attractive alternative to open surgery for pediatric renal tumors.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Laparoscopy
/
Wilms Tumor
/
Kidney Neoplasms
/
Nephrectomy
Limits:
Child
/
Humans
Language:
En
Journal:
J Biol Regul Homeost Agents
Journal subject:
BIOLOGIA
/
BIOQUIMICA
Year:
2019
Document type:
Article
Affiliation country:
Italy