Lethal and mutagenic bystander effects in human fibroblast cell cultures subjected to low-energy-carbon ions.

Suzuki, Masao; Yasuda, Nakahiro; Kitamura, Hisashi

Suzuki, Masao; Yasuda, Nakahiro; Kitamura, Hisashi.

Affiliation

Suzuki M; Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Yasuda N; Research Institute of Nuclear Engineering, University of Fukui, Tsuruga, Japan.
Kitamura H; Department of Radiation Measurement and Dose Assessment, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Int J Radiat Biol ; 96(2): 179-186, 2020 02.

Article in En | MEDLINE | ID: mdl-31633439

Subject(s)

Bystander Effect/radiation effects; Cell Survival/radiation effects; Fibroblasts/radiation effects; Gap Junctions/radiation effects; Heavy Ion Radiotherapy/methods; Mutagenesis; Carbon/chemistry; Cell Culture Techniques; DNA Damage; Dose-Response Relationship, Radiation; Heavy Ions; Humans; Hypoxanthine Phosphoribosyltransferase/genetics; Ions; Linear Energy Transfer; Mutagens; Mutation

Key words

HPRT mutation; Low-energy heavy ions; bystander effects; cell death; gap-junction mediated cell-cell communication

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Survival / Mutagenesis / Gap Junctions / Bystander Effect / Fibroblasts / Heavy Ion Radiotherapy Limits: Humans Language: En Journal: Int J Radiat Biol Journal subject: RADIOLOGIA Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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