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Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib.
Hassan, Mohammed; Butler, Erin; Wilson, Raphael; Roy, Angshumoy; Zheng, Yanbin; Liem, Priscilla; Rakheja, Dinesh; Pavlick, Dean; Young, Lauren L; Rosenzweig, Mark; Erlich, Rachel; Ali, Siraj M; Leavey, Patrick J; Parsons, D Williams; Skapek, Stephen X; Laetsch, Theodore W.
Affiliation
  • Hassan M; Division of Hematology/Oncology, Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Butler E; Division of Hematology/Oncology, Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Wilson R; Pauline Allen Gill Center for Cancer and Blood Disorders, Children's Health, Dallas, Texas 75235, USA.
  • Roy A; Division of Hematology/Oncology, Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Zheng Y; Baylor College of Medicine, Houston, Texas 77030, USA.
  • Liem P; Division of Hematology/Oncology, Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Rakheja D; Division of Hematology/Oncology, Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Pavlick D; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Young LL; Foundation Medicine, Inc, Cambridge, Massachusetts 02141, USA.
  • Rosenzweig M; Foundation Medicine, Inc, Cambridge, Massachusetts 02141, USA.
  • Erlich R; Beam Therapeutics, Cambridge, Massachusetts 02139, USA.
  • Ali SM; Foundation Medicine, Inc, Cambridge, Massachusetts 02141, USA.
  • Leavey PJ; Foundation Medicine, Inc, Cambridge, Massachusetts 02141, USA.
  • Parsons DW; Foundation Medicine, Inc, Cambridge, Massachusetts 02141, USA.
  • Skapek SX; Division of Hematology/Oncology, Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  • Laetsch TW; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
Article in En | MEDLINE | ID: mdl-31645346

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myofibromatosis / Receptor, Platelet-Derived Growth Factor beta / Imatinib Mesylate Type of study: Diagnostic_studies Limits: Animals / Female / Humans / Newborn Language: En Journal: Cold Spring Harb Mol Case Stud Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myofibromatosis / Receptor, Platelet-Derived Growth Factor beta / Imatinib Mesylate Type of study: Diagnostic_studies Limits: Animals / Female / Humans / Newborn Language: En Journal: Cold Spring Harb Mol Case Stud Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States