MicroRNA-381 inhibits lung adenocarcinoma cell biological progression by directly targeting LMO3 through regulation of the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition.

Xuan, Y-W; Liao, M; Zhai, W-L; Peng, L-J; Tang, Y

Xuan, Y-W; Liao, M; Zhai, W-L; Peng, L-J; Tang, Y.

Affiliation

Xuan YW; Department of Thoracic Surgery, General Hospital of Southern Theatre Command, Guangzhou, China. ywz1112@sina.com.

Eur Rev Med Pharmacol Sci ; 23(19): 8411-8421, 2019 Oct.

Article in En | MEDLINE | ID: mdl-31646571

Subject(s)

Adenocarcinoma of Lung/metabolism; Epithelial-Mesenchymal Transition; Lung Neoplasms/metabolism; MicroRNAs/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Adaptor Proteins, Signal Transducing; Adenocarcinoma of Lung/genetics; Adenocarcinoma of Lung/pathology; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Epithelial-Mesenchymal Transition/genetics; Female; Humans; LIM Domain Proteins; Lung Neoplasms/genetics; Lung Neoplasms/pathology; Mice; Mice, Nude; MicroRNAs/genetics; Neoplasms, Experimental/genetics; Neoplasms, Experimental/metabolism; Neoplasms, Experimental/pathology; Signal Transduction

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidylinositol 3-Kinases / MicroRNAs / Proto-Oncogene Proteins c-akt / Epithelial-Mesenchymal Transition / Adenocarcinoma of Lung / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Eur Rev Med Pharmacol Sci Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2019 Document type: Article Affiliation country: China Country of publication: Italy

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google