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Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys.
Ye, Qiuji; Chourey, Shishir; Reddy, Chintam Nagendra; Wang, Rui; Cossette, Chantal; Gravel, Sylvie; Slobodchikova, Irina; Vuckovic, Dajana; Rokach, Joshua; Powell, William S.
Affiliation
  • Ye Q; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
  • Chourey S; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
  • Reddy CN; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
  • Wang R; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
  • Cossette C; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, QC, Canada.
  • Gravel S; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, QC, Canada.
  • Slobodchikova I; Department of Chemistry and Biochemistry and PERFORM Centre, Concordia University, Montreal, QC, Canada.
  • Vuckovic D; Department of Chemistry and Biochemistry and PERFORM Centre, Concordia University, Montreal, QC, Canada.
  • Rokach J; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
  • Powell WS; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, QC, Canada.
Br J Pharmacol ; 177(2): 388-401, 2020 01.
Article in En | MEDLINE | ID: mdl-31655025
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Eicosanoid / Anti-Allergic Agents / Indoles / Anti-Inflammatory Agents / Neutrophils Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Br J Pharmacol Year: 2020 Document type: Article Country of publication: United kingdom
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Eicosanoid / Anti-Allergic Agents / Indoles / Anti-Inflammatory Agents / Neutrophils Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Br J Pharmacol Year: 2020 Document type: Article Country of publication: United kingdom