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Heterogeneity of cell therapy products.
Wolmarans, E; Mellet, J; Ambele, M A; Durandt, C; Pepper, M S.
Affiliation
  • Wolmarans E; Institute for Cellular and Molecular Medicine, Department of Immunology and South African Medical Research Council Extramural Unit for Stem Cell Research and Therapy, Faculty of Health Sciences, University of Pretoria, South Africa. elizewol@yahoo.com.
S Afr Med J ; 109(8b): 24-28, 2019 Sep 10.
Article in En | MEDLINE | ID: mdl-31662145
ABSTRACT
Cellular therapy has become a billion-dollar industry and is set to become one of the therapeutic pillars of healthcare in the 21st century. Adult stem cells, which include haematopoietic stem and progenitor cells (HSPCs) and mesenchymal stromal/stem cells (MSCs), is one of the major cell types currently under investigation for use in cell therapy. This review focuses on HSPCs and MSCs and discusses their heterogeneous nature and the problems faced in expanding these cells to therapeutic numbers for use in clinical applications.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Hematopoietic Stem Cell Transplantation / Mesenchymal Stem Cell Transplantation / Mesenchymal Stem Cells Limits: Adult / Animals / Humans Language: En Journal: S Afr Med J Year: 2019 Document type: Article Affiliation country: South Africa
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Hematopoietic Stem Cell Transplantation / Mesenchymal Stem Cell Transplantation / Mesenchymal Stem Cells Limits: Adult / Animals / Humans Language: En Journal: S Afr Med J Year: 2019 Document type: Article Affiliation country: South Africa