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Inhibition of nitric oxide and prostaglandin E2 production by pyrrolylated-chalcones: Synthesis, biological activity, crystal structure analysis, and molecular docking studies.
Mohd Faudzi, Siti Munirah; Abdullah, Maryam Aisyah; Abdull Manap, Mohd Rashidi; Ismail, Ahmad Zaidi; Rullah, Kamal; Mohd Aluwi, Mohd Fadhlizil Fasihi; Mazila Ramli, Aizi Nor; Abas, Faridah; Lajis, Nordin H.
Affiliation
  • Mohd Faudzi SM; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. Electronic address: sitimunirah@upm.edu.my.
  • Abdullah MA; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
  • Abdull Manap MR; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
  • Ismail AZ; Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
  • Rullah K; Department of Pharmaceutical Chemistry, Kuliyyah of Pharmacy, International Islamic University Malaysia, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia.
  • Mohd Aluwi MFF; Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak, Gambang, Kuantan 26300, Pahang, Malaysia.
  • Mazila Ramli AN; Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak, Gambang, Kuantan 26300, Pahang, Malaysia.
  • Abas F; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia; Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
  • Lajis NH; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Bioorg Chem ; 94: 103376, 2020 01.
Article in En | MEDLINE | ID: mdl-31677861
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Dinoprostone / Anti-Inflammatory Agents, Non-Steroidal / Chalcones / Molecular Docking Simulation / Nitric Oxide Limits: Animals / Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Dinoprostone / Anti-Inflammatory Agents, Non-Steroidal / Chalcones / Molecular Docking Simulation / Nitric Oxide Limits: Animals / Humans Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Country of publication: United States