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Downregulation of PHGDH expression and hepatic serine level contribute to the development of fatty liver disease.
Sim, Woo-Cheol; Lee, Wonseok; Sim, Hyungtai; Lee, Kang-Yo; Jung, Seung-Hwan; Choi, You-Jin; Kim, Hyun Young; Kang, Keon Wook; Lee, Ji-Yoon; Choi, Young Jae; Kim, Sang Kyum; Jun, Dae Won; Kim, Won; Lee, Byung-Hoon.
Affiliation
  • Sim WC; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Lee W; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Sim H; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Lee KY; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Jung SH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Choi YJ; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Kim HY; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Kang KW; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
  • Lee JY; College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
  • Choi YJ; College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
  • Kim SK; College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
  • Jun DW; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.
  • Kim W; Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
  • Lee BH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea. Electronic address: lee@snu.ac.kr.
Metabolism ; 102: 154000, 2020 01.
Article in En | MEDLINE | ID: mdl-31678070

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine / Non-alcoholic Fatty Liver Disease / Glyceraldehyde-3-Phosphate Dehydrogenases / Liver Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Metabolism Year: 2020 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine / Non-alcoholic Fatty Liver Disease / Glyceraldehyde-3-Phosphate Dehydrogenases / Liver Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Metabolism Year: 2020 Document type: Article Country of publication: United States