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LCP1 triggers mTORC2/AKT activity and is pharmacologically targeted by enzastaurin in hypereosinophilia.
Ma, Guangxin; Gezer, Deniz; Herrmann, Oliver; Feldberg, Kristina; Schemionek, Mirle; Jawhar, Mohamad; Reiter, Andreas; Brümmendorf, Tim H; Koschmieder, Steffen; Chatain, Nicolas.
Affiliation
  • Ma G; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Gezer D; Hematology and Oncology Unit, Department of Geriatrics, Qilu Hospital of Shandong University, Jinan, Shandong, China.
  • Herrmann O; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Feldberg K; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Schemionek M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Jawhar M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Reiter A; Department of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
  • Brümmendorf TH; Department of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
  • Koschmieder S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
  • Chatain N; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Mol Carcinog ; 59(1): 87-103, 2020 01.
Article in En | MEDLINE | ID: mdl-31691359
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hypereosinophilic Syndrome / Protein Kinase Inhibitors / Proto-Oncogene Proteins c-akt / Mechanistic Target of Rapamycin Complex 2 / Indoles / Microfilament Proteins Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Germany Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hypereosinophilic Syndrome / Protein Kinase Inhibitors / Proto-Oncogene Proteins c-akt / Mechanistic Target of Rapamycin Complex 2 / Indoles / Microfilament Proteins Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Mol Carcinog Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Germany Country of publication: United States