The role of presepsin in the diagnosis of chronic obstructive pulmonary disease acute exacerbation with pneumonia.
Biomark Med
; 14(1): 31-41, 2020 01.
Article
in En
| MEDLINE
| ID: mdl-31701761
ABSTRACT
Aim:
In this study, we aimed to investigate the role of presepsin in detecting concomitant pneumonia in patients presenting with acute exacerbation of chronic obstructive pulmonary disease (COPD) in the emergency department. Patients &methods:
Three groups were formed in the study. Group 1 patients diagnosed with acute exacerbation of COPD; group 2 patients with acute exacerbation of COPD + pneumonia; group 3 healthy individuals.Results:
Presepsin levels of the patients in group 2 were significantly higher than those of group 1 and group 3 (p < 0.05). There was a statistically significant difference in erythrocyte sedimentation rate, CRP, procalcitonin and presepsin values between two patient groups (p < 0.05).Conclusion:
Presepsin can be used to diagnose pneumonia in patients with acute exacerbation of COPD admitted to the emergency department.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Peptide Fragments
/
Pneumonia
/
Biomarkers
/
Lipopolysaccharide Receptors
/
Pulmonary Disease, Chronic Obstructive
/
Emergency Service, Hospital
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Biomark Med
Journal subject:
BIOQUIMICA
/
MEDICINA
Year:
2020
Document type:
Article
Affiliation country:
Turkey