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The urinary metabolic profile of diethylene glycol methyl ether and triethylene glycol methyl ether in Sprague-Dawley rats and the role of the metabolite methoxyacetic acid in their toxicity.
Kelsey, Jeffrey R; Cnubben, Nicole H P; Bogaards, Jan J P; Braakman, René B H; van Stee, Leo L P; Smet, Karen.
Affiliation
  • Kelsey JR; Chemsage Ltd, PO Box 431, Fleet, Hampshire, GU51 9BP, UK. Electronic address: kelseyjr@chemsage.co.uk.
  • Cnubben NHP; Triskelion BV, Postal Address: P.O. Box 844, 3700 AV, Zeist, the Netherlands. Electronic address: nicole.cnubben@gmail.com.
  • Bogaards JJP; Triskelion BV, Postal Address: P.O. Box 844, 3700 AV, Zeist, the Netherlands. Electronic address: jan.bogaards@triskelion.nl.
  • Braakman RBH; Triskelion BV, Postal Address: P.O. Box 844, 3700 AV, Zeist, the Netherlands. Electronic address: rene.braakman@tno.nl.
  • van Stee LLP; Triskelion BV, Postal Address: P.O. Box 844, 3700 AV, Zeist, the Netherlands. Electronic address: leo.vanstee@triskelion.nl.
  • Smet K; Ineos Oxide, Safety, Health and Environment, Nieuwe Weg 1, 2070, Zwijndrecht, Belgium. Electronic address: karen.smet@ineos.com.
Regul Toxicol Pharmacol ; 110: 104512, 2020 Feb.
Article in En | MEDLINE | ID: mdl-31704259
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Solvents / Ethylene Glycols / Acetates / Methyl Ethers Limits: Animals Language: En Journal: Regul Toxicol Pharmacol Year: 2020 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Solvents / Ethylene Glycols / Acetates / Methyl Ethers Limits: Animals Language: En Journal: Regul Toxicol Pharmacol Year: 2020 Document type: Article