Efficacy and safety of subcutaneous administration of ceftazidime as a salvage therapy in geriatrics: a case report.
Fundam Clin Pharmacol
; 34(4): 521-524, 2020 Aug.
Article
in En
| MEDLINE
| ID: mdl-31709583
ABSTRACT
Ceftazidime is a third-generation cephalosporin used for the treatment of Gram-negative bacteria only approved for parenteral use by intravenous and intramuscular route. In some clinical situations, off-label subcutaneous injection could be a salvage route for the administration of antibiotics, especially in geriatrics, despite the paucity of evidence about efficacy and safety. We report a case of a successful and well-tolerated subcutaneous ceftazidime therapy in a 90-year-old woman for the treatment of an acute urinary tract infection caused by Pseudomonas aeruginosa with therapeutic drug monitoring data.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pseudomonas Infections
/
Urinary Tract Infections
/
Ceftazidime
/
Anti-Bacterial Agents
Type of study:
Diagnostic_studies
Limits:
Aged80
/
Female
/
Humans
Language:
En
Journal:
Fundam Clin Pharmacol
Journal subject:
FARMACOLOGIA
Year:
2020
Document type:
Article
Affiliation country:
France