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Alterations in plasma membrane ion channel structures stimulate NLRP3 inflammasome activation in APOL1 risk milieu.
Jha, Alok; Kumar, Vinod; Haque, Shabirul; Ayasolla, Kamesh; Saha, Shourav; Lan, Xiqian; Malhotra, Ashwani; Saleem, Moin A; Skorecki, Karl; Singhal, Pravin C.
Affiliation
  • Jha A; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
  • Kumar V; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
  • Haque S; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
  • Ayasolla K; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
  • Saha S; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
  • Lan X; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
  • Malhotra A; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
  • Saleem MA; Academic Renal Unit, University of Bristol, UK.
  • Skorecki K; Technion - Israel Institute of Technology, Rambam Health Care Campus, Haifa, Israel.
  • Singhal PC; Institute of Molecular Medicine, Feinstein Institute for Medical Research, Zucker School of Medicine at Hofstra-North Well, Manhasset, NY, USA.
FEBS J ; 287(10): 2000-2022, 2020 05.
Article in En | MEDLINE | ID: mdl-31714001

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Apolipoprotein L1 / Ion Channels Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: FEBS J Journal subject: BIOQUIMICA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Apolipoprotein L1 / Ion Channels Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: FEBS J Journal subject: BIOQUIMICA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom