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Cis/Trans Isomerization of Unsaturated Fatty Acids in Polysorbate 80 During Light Exposure of a Monoclonal Antibody-Containing Formulation.
Prajapati, Indira; Peters, Björn-Hendrik; Larson, Nicholas R; Wei, Yangjie; Choudhary, Sureshkumar; Kalonia, Cavan; Hudak, Suzanne; Esfandiary, Reza; Middaugh, C Russell; Schöneich, Christian.
Affiliation
  • Prajapati I; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047.
  • Peters BH; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047.
  • Larson NR; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047.
  • Wei Y; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047.
  • Choudhary S; Department of Dosage Form and Design Development, AstraZeneca, Gaithersburg, Maryland 20878.
  • Kalonia C; Department of Dosage Form and Design Development, AstraZeneca, Gaithersburg, Maryland 20878.
  • Hudak S; Department of Dosage Form and Design Development, AstraZeneca, Gaithersburg, Maryland 20878.
  • Esfandiary R; Department of Dosage Form and Design Development, AstraZeneca, Gaithersburg, Maryland 20878.
  • Middaugh CR; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047.
  • Schöneich C; Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047. Electronic address: schoneic@ku.edu.
J Pharm Sci ; 109(1): 603-613, 2020 01.
Article in En | MEDLINE | ID: mdl-31715179
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysorbates / Oleic Acids / Linoleic Acids, Conjugated / Antibodies, Monoclonal Language: En Journal: J Pharm Sci Year: 2020 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysorbates / Oleic Acids / Linoleic Acids, Conjugated / Antibodies, Monoclonal Language: En Journal: J Pharm Sci Year: 2020 Document type: Article Country of publication: United States