Functional signs in patients consulting for presumed Lyme borreliosis.
Med Mal Infect
; 50(5): 423-427, 2020 Aug.
Article
in En
| MEDLINE
| ID: mdl-31722861
ABSTRACT
INTRODUCTION:
Little is known about the functional symptoms associated with Lyme borreliosis (LB) in Europe. We aimed to assess functional symptoms associated with presumed LB and to compare patients with and without confirmed LB. MATERIALS ANDMETHODS:
We performed a retrospective monocenter study. Patients consulting for presumed LB were included.RESULTS:
Between November 2015 and June 2018, 355patients were included (mean age 51years, 52% of women) of which 48had LB erythema migrans (42%), early disseminated LB (50%; 35% of neuroborreliosis cases), and late disseminated LB (8%). The most frequently reported functional symptoms were neuropathic pain (23%), arthralgia (23%), and asthenia (17%). Other functional symptoms were rare (≤10%). Three hundred and seven (86%) patients did not have LB. Patients with confirmed LB reported fewer functional symptoms than patients without LB (1.8 (±1.7) vs. 3.6 (±2.5), P<0.001) with a shorter duration of symptoms (< 3 months in 48% vs. 16% of cases, P<0.001). They less often reported asthenia (17% vs. 59%, P<0.001), widespread pain (10% vs. 31%, P=0.003), myalgia (10% vs. 32%, P=0.002), memory disorders (4% vs. 16%, P=0.03), irritability (2% vs. 23%, P±0.001), and sadness (0% vs. 16%, P=0.003).CONCLUSION:
In patients consulting for presumed LB, patients diagnosed with LB had fewer and shorter functional symptoms than patients without LB.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Lyme Disease
/
Symptom Assessment
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
Med Mal Infect
Year:
2020
Document type:
Article
Affiliation country:
France