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Design and synthesis of α-phenoxy-N-sulfonylphenyl acetamides as Trypanosoma brucei Leucyl-tRNA synthetase inhibitors.
Xin, Weixiang; Li, Zezhong; Wang, Qing; Du, Jin; Zhu, Mingyan; Zhou, Huchen.
Affiliation
  • Xin W; State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
  • Li Z; State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
  • Wang Q; State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
  • Du J; State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
  • Zhu M; State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China.
  • Zhou H; State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China. Electronic address: hczhou@sjtu.edu.cn.
Eur J Med Chem ; 185: 111827, 2020 Jan 01.
Article in En | MEDLINE | ID: mdl-31732256
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanocidal Agents / Trypanosoma brucei brucei / Drug Design / Enzyme Inhibitors / Leucine-tRNA Ligase / Acetamides Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Country of publication: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanocidal Agents / Trypanosoma brucei brucei / Drug Design / Enzyme Inhibitors / Leucine-tRNA Ligase / Acetamides Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Country of publication: France