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Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria.
Dokla, Eman M E; Abutaleb, Nader S; Milik, Sandra N; Li, Daoyi; El-Baz, Karim; Shalaby, Menna-Allah W; Al-Karaki, Rawan; Nasr, Maha; Klein, Christian D; Abouzid, Khaled A M; Seleem, Mohamed N.
Affiliation
  • Dokla EME; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt. Electronic address: emanelawady@pharma.asu.edu.eg.
  • Abutaleb NS; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, 47907, USA.
  • Milik SN; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt; Medicinal Chemistry, Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, Im Neuenheimer Feld 364, 69120, Heidelberg, Germany.
  • Li D; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, 47907, USA.
  • El-Baz K; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt; Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST), Hwarangro 14-gil 5, Seongbuk-gu, Seoul, 136-791, Republic of Korea; Division of Bio-Med
  • Shalaby MW; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
  • Al-Karaki R; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Mutah University, Karak, 61710, Jordan.
  • Nasr M; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
  • Klein CD; Medicinal Chemistry, Institute of Pharmacy and Molecular Biotechnology (IPMB), Heidelberg University, Im Neuenheimer Feld 364, 69120, Heidelberg, Germany.
  • Abouzid KAM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, 11566, Egypt; Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Sadat City, 32897, Egypt.
  • Seleem MN; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, 47907, USA; Purdue Institute of Inflammation, Immunology, and Infectious Disease, West Lafayette, IN, 47907, USA. Electronic address: mseleem@purdue.edu.
Eur J Med Chem ; 186: 111850, 2020 Jan 15.
Article in En | MEDLINE | ID: mdl-31735572
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Colistin / Gram-Negative Bacteria / Anti-Bacterial Agents Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Colistin / Gram-Negative Bacteria / Anti-Bacterial Agents Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article