MBD-seq - realities of a misunderstood method for high-quality methylome-wide association studies.

Aberg, Karolina A; Chan, Robin F; van den Oord, Edwin J C G

Aberg, Karolina A; Chan, Robin F; van den Oord, Edwin J C G.

Affiliation

Aberg KA; Center for Biomarker Research and Precision Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, USA.
Chan RF; Center for Biomarker Research and Precision Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, USA.
van den Oord EJCG; Center for Biomarker Research and Precision Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, USA.

Epigenetics ; 15(4): 431-438, 2020 04.

Article in En | MEDLINE | ID: mdl-31739727

Subject(s)

Epigenome; Epigenomics/methods; Genome-Wide Association Study/methods; Sequence Analysis, DNA/methods; CpG Islands; Epigenomics/standards; Genome-Wide Association Study/standards; Humans; Sensitivity and Specificity; Sequence Analysis, DNA/standards; Software

Key words

DNA methylation; Epigenetics; MBD-seq; RaMWAS software; epigenome-wide association study (EWAS); methyl-binding domain sequencing; methylome-wide association study (MWAS)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sequence Analysis, DNA / Genome-Wide Association Study / Epigenomics / Epigenome Type of study: Diagnostic_studies / Evaluation_studies / Risk_factors_studies Limits: Humans Language: En Journal: Epigenetics Journal subject: GENETICA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States

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