AID Phosphorylation Regulates Mismatch Repair-Dependent Class Switch Recombination and Affinity Maturation.

Choi, Jee Eun; Matthews, Allysia J; Michel, Genesis; Vuong, Bao Q

Choi, Jee Eun; Matthews, Allysia J; Michel, Genesis; Vuong, Bao Q.

Affiliation

Choi JE; The City College of New York, The City University of New York, New York, NY 10031; and.
Matthews AJ; The City College of New York, The City University of New York, New York, NY 10031; and.
Michel G; The City College of New York, The City University of New York, New York, NY 10031; and.
Vuong BQ; The Graduate Center, The City University of New York, New York, NY 10016 bvuong@ccny.cuny.edu.

J Immunol ; 204(1): 13-22, 2020 01 01.

Article in En | MEDLINE | ID: mdl-31757865

Subject(s)

Cytidine Deaminase/genetics; Cytidine Deaminase/metabolism; DNA Mismatch Repair/genetics; Immunoglobulin Class Switching/genetics; Somatic Hypermutation, Immunoglobulin/genetics; Animals; B-Lymphocytes/cytology; B-Lymphocytes/immunology; DNA Breaks, Double-Stranded; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism; Female; Genes, Immunoglobulin/genetics; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MutS Homolog 2 Protein/genetics; Phosphorylation; Recombination, Genetic; Uracil-DNA Glycosidase/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Class Switching / Cytidine Deaminase / Somatic Hypermutation, Immunoglobulin / DNA Mismatch Repair Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2020 Document type: Article Country of publication: United States

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