Parent reported health related quality of life (HRQoL) and behaviour in young people with epilepsy before and two years after epilepsy surgery.
Seizure
; 74: 1-7, 2020 Jan.
Article
in En
| MEDLINE
| ID: mdl-31760145
ABSTRACT
PURPOSE:
The aim of this study was to compare parent-reported Health Related Quality of Life (HRQoL) and behaviour of young people before (baseline) and two years after paediatric epilepsy surgery (follow-up).METHODS:
The parents of 107 children who underwent epilepsy surgery completed surveys focussing on different aspects of child HRQoL and behaviour at baseline and follow-up. Parents of children with multiple disabilities (nâ¯=â¯27) completed five additional questions focussing on child HRQoL. Changes in scores between baseline and follow-up were compared using Wilcoxon signed-rank tests. Factors associated with changes in scores were analyzed using linear regression.RESULTS:
HRQoL and behaviour were significantly improved at follow-up (pâ¯<â¯0.001). HRQoL was also significantly improved for children with multiple disabilities (pâ¯=â¯0.003). Factors independently associated with improvement in HRQoL on multivariable analysis were lower baseline scores (pâ¯<â¯0.001), seizure-free status (pâ¯<â¯0.001) and improvement in behaviour (pâ¯=â¯0.022). Factors independently associated with improvement in behaviour were higher baseline difficulties (pâ¯<â¯0.001), reduction in antiepileptic drug (AED) usage, (pâ¯<â¯0.001), seizure-free status (pâ¯=â¯0.04), younger age (pâ¯=â¯0.03), and improvements in HRQoL (pâ¯=â¯0.028).CONCLUSION:
Parent rated HRQoL and behaviour had improved two years after epilepsy surgery. Seizure freedom was associated with both improvements in HRQoL and behaviour. Additionally, a reduction in AED usage contributed to reduced behavioural difficulties. All children undergoing epilepsy surgery should undergo assessment of HRQoL and behaviour at baseline and follow-up.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parents
/
Quality of Life
/
Child Behavior
/
Surveys and Questionnaires
/
Adolescent Behavior
/
Epilepsy
Type of study:
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Seizure
Journal subject:
NEUROLOGIA
Year:
2020
Document type:
Article