Antiproliferative and Apoptotic Properties of Andrographolide Against Human Colon Cancer DLD1 Cell Line.

Khan, Imran; Mahfooz, Sadaf; Ansari, Irfan A

Khan, Imran; Mahfooz, Sadaf; Ansari, Irfan A.

Affiliation

Khan I; Department of Molecular Biology, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Yaliköy Mahallesi, Beykoz, Istanbul, Turkey
Mahfooz S; Department of Biosciences, Integral University, Dasauli, Kursi Road, Lucknow, 226026, India
Ansari IA; Department of Molecular Biology, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Yaliköy Mahallesi, Beykoz, Istanbul, Turkey

Endocr Metab Immune Disord Drug Targets ; 20(6): 930-942, 2020.

Article in En | MEDLINE | ID: mdl-31774047

Subject(s)

Apoptosis/drug effects; Cell Proliferation/drug effects; Colonic Neoplasms/pathology; Diterpenes/pharmacology; Animals; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Cell Survival/drug effects; Cells, Cultured; Colonic Neoplasms/metabolism; Humans; Intestinal Mucosa/cytology; Intestinal Mucosa/drug effects; Intestinal Mucosa/physiology; Intestine, Small/drug effects; Intestine, Small/physiology; Rats; Reactive Oxygen Species/metabolism

Key words

Andrographolide; DLD1; apoptosis; chemopreventive; colon cancer; synergistic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Colonic Neoplasms / Cell Proliferation / Diterpenes Limits: Animals / Humans Language: En Journal: Endocr Metab Immune Disord Drug Targets Journal subject: ALERGIA E IMUNOLOGIA / ENDOCRINOLOGIA / METABOLISMO / TERAPIA POR MEDICAMENTOS Year: 2020 Document type: Article Affiliation country: Turkey Country of publication: United Arab Emirates

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