Aging alters Hv1-mediated microglial polarization and enhances neuroinflammation after peripheral surgery.

Zhang, Zhi-Jing; Zheng, Xin-Xun; Zhang, Xin-Yun; Zhang, Yi; Huang, Bao-Yi; Luo, Tao

Zhang, Zhi-Jing; Zheng, Xin-Xun; Zhang, Xin-Yun; Zhang, Yi; Huang, Bao-Yi; Luo, Tao.

Affiliation

Zhang ZJ; Department of Anesthesiology, Peking University Shenzhen Hospital, Shenzhen, China.
Zheng XX; Shantou University Medical College, Shantou, China.
Zhang XY; Department of Anesthesiology, Peking University Shenzhen Hospital, Shenzhen, China.
Zhang Y; Department of Anesthesiology, Peking University Shenzhen Hospital, Shenzhen, China.
Huang BY; Shantou University Medical College, Shantou, China.
Luo T; Department of Anesthesiology, Peking University Shenzhen Hospital, Shenzhen, China.

CNS Neurosci Ther ; 26(3): 374-384, 2020 03.

Article in En | MEDLINE | ID: mdl-31774629

Subject(s)

Aging/metabolism; Cell Polarity/physiology; Fracture Fixation/adverse effects; Inflammation Mediators/metabolism; Ion Channels/biosynthesis; Microglia/metabolism; Aging/immunology; Animals; Immunity, Innate/physiology; Inflammation/etiology; Inflammation/immunology; Inflammation/metabolism; Inflammation Mediators/immunology; Ion Channels/immunology; Male; Mice; Mice, Inbred C57BL; Microglia/immunology; Tibial Fractures/immunology; Tibial Fractures/metabolism; Tibial Fractures/surgery

Key words

Hv1; aging; microglial polarization; neuroinflammation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Cell Polarity / Microglia / Inflammation Mediators / Fracture Fixation / Ion Channels Type of study: Etiology_studies / Risk_factors_studies Limits: Animals Language: En Journal: CNS Neurosci Ther Journal subject: NEUROLOGIA / TERAPEUTICA Year: 2020 Document type: Article Affiliation country: China

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