Bone and joint pathology in fluoride-exposed workers.
Arch Environ Health
; 43(5): 340-3, 1988.
Article
in En
| MEDLINE
| ID: mdl-3178291
ABSTRACT
Clinical and radiological investigations were performed for 2,258 aluminum workers exposed to fluoride for an average of 17.6 yr (standard deviation = 7.6). Changes in bone and joints were presented in detail in three groups (1) exposed up to 5 yr (135 cases), (2) exposed from 6-32 yr (1,463 cases), and (3) retired workers (660 cases). A semiquantitative assessment of early fluorosis was introduced. A 20.2% incidence of fluorosis was found, but, according to Roholm, only 1.05% was in stage I. The disease was mainly in the pre-stages of O and OI. A close relationship between the occurrence of fluorosis and the time and degree of fluoride exposure was found. The difficulties in diagnosing skeletal fluorosis result from the questionable sensitivity of the x-ray techniques and from the nonspecificity of the associated symptoms. A quantitative method to assess osteosclerosis and bone structure alteration is needed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteosclerosis
/
Fluoride Poisoning
/
Occupational Diseases
Type of study:
Diagnostic_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
Arch Environ Health
Year:
1988
Document type:
Article
Affiliation country:
Poland