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Loss of TOP3B leads to increased R-loop formation and genome instability.
Zhang, Tao; Wallis, Mathew; Petrovic, Vida; Challis, Jackie; Kalitsis, Paul; Hudson, Damien F.
Affiliation
  • Zhang T; Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Victoria 3052, Australia.
  • Wallis M; Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria 3052, Australia.
  • Petrovic V; Tasmanian Clinical Genetics Services, Royal Hobart Hospital, Hobart, Tasmania 7001, Australia.
  • Challis J; School of Medicine and Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania 7001, Australia.
  • Kalitsis P; Cytogenetics Department, Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria 3052, Australia.
  • Hudson DF; Cytogenetics Department, Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria 3052, Australia.
Open Biol ; 9(12): 190222, 2019 12.
Article in En | MEDLINE | ID: mdl-31795919
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Topoisomerases, Type I / Genomic Instability / R-Loop Structures Limits: Humans Language: En Journal: Open Biol Year: 2019 Document type: Article Affiliation country: Australia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Topoisomerases, Type I / Genomic Instability / R-Loop Structures Limits: Humans Language: En Journal: Open Biol Year: 2019 Document type: Article Affiliation country: Australia