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Light-responsive vesicles for enantioselective release of chiral drugs prepared from a supra-amphiphilic M-helix.
Yan, Tengfei; Li, Fei; Qi, Shuaiwei; Tian, Jun; Tian, Ruizhen; Hou, Jinxing; Luo, Quan; Dong, Zeyuan; Xu, Jiayun; Liu, Junqiu.
Affiliation
  • Yan T; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Li F; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Qi S; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Tian J; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Tian R; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Hou J; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Luo Q; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Dong Z; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Xu J; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
  • Liu J; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. junqiuliu@jlu.edu.cn.
Chem Commun (Camb) ; 56(1): 149-152, 2020 Jan 04.
Article in En | MEDLINE | ID: mdl-31799973
ABSTRACT
A kind of light-responsive vesicle was prepared by aqueous self-assembly of α-CD and an azobenzene-containing M-helical foldamer, which displayed dynamic disassembly-reassembly structural transformation when alternately irradiated by UV and visible light. Distinctively, this vesicle also exhibited enantioselective release abilities toward racemic propranolol (a ß-blocker), owing to the M-helical building blocks.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Carriers / Alpha-Cyclodextrins / Liposomes Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Carriers / Alpha-Cyclodextrins / Liposomes Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: China