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Evaluating the role of ENOSF1 and TYMS variants as predictors in fluoropyrimidine-related toxicities: An IPD meta-analysis.
Hamzic, Seid; Kummer, Dominic; Froehlich, Tanja K; Joerger, Markus; Aebi, Stefan; Palles, Claire; Thomlinson, Ian; Meulendijks, Didier; Schellens, Jan H M; García-González, Xandra; López-Fernández, Luis A; Amstutz, Ursula; Largiadèr, Carlo R.
Affiliation
  • Hamzic S; University Institute of Clinical Chemistry, University of Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Freiestrasse 1, CH-3012, Bern, Switzerland.
  • Kummer D; University Institute of Clinical Chemistry, University of Bern, Switzerland.
  • Froehlich TK; University Institute of Clinical Chemistry, University of Bern, Switzerland.
  • Joerger M; Department of Medical Oncology and Hematology, Cantonal Hospital St. Gallen, Rorschacherstrasse 95, CH-9007, St. Gallen, Switzerland.
  • Aebi S; Division of Medical Oncology, Cantonal Hospital Lucerne, Spitalstrasse, CH-6000, Lucerne 16, Switzerland.
  • Palles C; Gastrointestinal Cancer Genetics, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Thomlinson I; Cancer Genetics and Evolution Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Meulendijks D; Dutch Medicines Evaluation Board (CBG-MEB), Utrecht, the Netherlands.
  • Schellens JHM; Faculty of Science, Utrecht University, Utrecht, the Netherlands.
  • García-González X; Pharmacy Department, Hospital General Universitario Gregorio Marañón, Gregorio Marañón Health Research Institute, Doctor Esquerdo 46, 28007, Madrid, Spain.
  • López-Fernández LA; Pharmacy Department, Hospital General Universitario Gregorio Marañón, Gregorio Marañón Health Research Institute, Doctor Esquerdo 46, 28007, Madrid, Spain; Spanish Clinical Research Network, Doctor Esquerdo 46, 28007, Madrid, Spain.
  • Amstutz U; University Institute of Clinical Chemistry, University of Bern, Switzerland.
  • Largiadèr CR; University Institute of Clinical Chemistry, University of Bern, Switzerland. Electronic address: carlo.largiader@insel.ch.
Pharmacol Res ; 152: 104594, 2020 02.
Article in En | MEDLINE | ID: mdl-31838077
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymidylate Synthase / Hand-Foot Syndrome / Capecitabine / Fluorouracil / Hydro-Lyases / Neoplasms / Antimetabolites, Antineoplastic Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: Switzerland Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymidylate Synthase / Hand-Foot Syndrome / Capecitabine / Fluorouracil / Hydro-Lyases / Neoplasms / Antimetabolites, Antineoplastic Type of study: Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: Switzerland Country of publication: Netherlands